Which term means pertaining to on or upon the muscles?

• A. Epimysium
• B. Endomysium
• C. Perimysium
• D. Fascia

Answer: (A)

Understanding muscle connective tissue names starts with location prefixes. “epi-” means on or upon, and “mys” is muscle. Epimysium is the outermost sheath that surrounds the entire muscle, literally sitting on the surface of the muscle itself. That direct meaning fits the description of being on or upon the muscles. In contrast, endomysium surrounds each individual muscle fiber inside the muscle, perimysium wraps fascicles of fibers, and fascia is a broader connective-tissue layer around groups of muscles. So the term that means on or upon the muscles is epimysium.